Vol 4-1 Mini Review

Perturbations in Cellular Bioenergetics: Childhood Obesity, Dyslipidemia, Diabetes and Hypoglycemia

Noura Al Hassani1, Abdul-Kader Souid2*

1Department of Pediatrics, Tawam Hospital, Alain, United Arab Emirates (UAE)

2Department of Pediatrics, College of Medicine and Health Sciences - UAE University, Alain, UAE

One-third of children and adolescents are currently classified as overweight or obese. This epidemic childhood disease is the origin of adult obesity and its associated cardiovascular diseases. Dyslipidemia is also well-recognized risk of cardiovascular disease that often starts in childhood. Breasfeeding lowers the risks of obesity and dyslipidemia later in life and it should be encouraged. Type 1 diabetes (T1D) is an immune-mediated destruction of the pancreatic islets. It is often associated with other autoimmune disorders, such as chronic lymphocytic thyroiditis and celiac disease. Children with T1D require insulin to ‎prevent fatty acid oxidation regardless of their blood glucose level. Exercise can induce hypoglycemia in a child with T1D, as glucose utilization and insulin sensitivity increase. Thus, children with T1D need to check their blood glucose before, during, and after the activity. Type 2 diabetes (T2D) represents an insulin deficiency due to obesity and genetic susceptibility; glucose is overproduced by the liver and underused by the muscles. Thus, healthy diet and regular exercise are the recommended remedies for this condition.

DOI: 10.29245/2578-2940/2020/1.1155 View / Download Pdf
Vol 4-1 Case Report

OEIS complex and diaphragmatic agenesis: a rare association

María Recuero Pradillo1*, Beatriz Moreno Torres1, Carlos Quimbayo-Arcila1, Esperanza Carabias Lopez1, Laura Sánchez Sánchez2, Ángel Pantoja2, Pedro Rafael Altungy Labrador3, Juan Ruiz Martín1

1Department of Pathology. Hospital Virgen de la Salud, Toledo, Spain

2Department of Pediatrics and Neonatology. Hospital Virgen de la Salud, Toledo, Spain

3Department of Research. Complutense University of Madrid, Spain

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