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Journal of Pediatrics and Pediatric Medicine is primarily based on values centered on loyalty, commitment, scientific accuracy, and ethics. It has adopted clear and rigorous ethical guidelines for best working practices.    Read More

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Each article we publish benefits from hundreds of hours of work by Chief editors, Sectional editors, Reviewers, Manuscript editors, Proofreaders, Graphics and Web experts, who work to ensure that the manuscript meets our standards.    Read More

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The Journal of Pediatrics and Pediatric Medicine is an International peer reviewed open access journal which aims to provide untainted and factual scientific information for the healthy tomorrows of infants, children and adolescents. The Journal of Pediatrics and Pediatric medicine continues to promote the latest expansions in pediatric medicine, child health, policy, and support.

The Journal provides a link between concept and preparation in the field. Papers account key results of clinical and public research, and considerations of programme development.

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It is the Foundation of our Publication”

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Recent Articles


Vol 2-3 Research

Treatment of congenital mesoblastic nephroma at pediatric oncology unit of Gabriel Toure teaching hospital

Fousseyni Traore1*, Belco Maiga1, Konimba Diabaté2, Yacaria Coulibaly3, Hawa Diall1, Pierre Togo1, Oumar Coulibaly1, Issa Amadou3, Karamoko Sacko1, Abdoul Karim Doumbia1, Abdoul Aziz Diakite1, Bakary Kamaté4, Fatoumata Dicko-Traoré1, Mariam Sylla1, Boubacar Togo1

1Gabriel Toure hospital, department of pediatrics, Bamako-Mali

2National hospital of Mali, Radiation therapy service, Bamako-Mali

3Gabriel Toure hospital, pediatric surgery service, Bamako-Mali

4Hospital of Point G, department of histopathology, Bamako-Mali

Purpose: Congenital mesoblastic nephroma (CMN) is a mesenchymal renal tumor of the newborn and young infant. This tumor is generally non-aggressive and amenable to surgical removal. Few studies are available in Africa about the treatment of CMN. The aim of this retrospective study was to evaluate the treatment of CMN in the pediatric oncology unit of teaching hospital Gabriel Toure in Bamako-Mali.

Patients and method: The study was performed retrospectively from 01 January 2005 to 31 December 2016 (duration 11 years), in the pediatric-oncology unit of Gabriel Touré Teaching Hospital. Were included, patients with histologically proven CMN. The uretero-nephrectomy was indicated for all included patients. Patients with significant tumor volume at abdominal CT-scan and those with no staging at surgery with imprecise histologic stage, received neoadjuvant and adjuvant chemotherapy, respectively.

Result:From 2005/01/01 to 2016/12/31 eight cases of CMN were included in the study. CMN accounted for 3% of renal tumors. The median age of patient was 4.5 months (1 month-6 months) with a sex ratio of 0.33 (M = 2, F = 6). Abdominal mass was the most common physical sign (n = 7; 87%). The CT scan was performed in five patients (62%). There was no difference in laterality (right kidney, n = 4, left kidney, n = 4).

Three patients received neoadjuvant chemotherapy (37%). Seventy-two percent of patients received initial nephro-ureterectomy. The histology confirmed CMN in all patients (n = 8, 100%). All patients had the classic histological form (n = 8; 100%). Stage 1 (n = 4; 50%), stage 2 (n = 2; 25%), unspecified (n = 2; 25%). Two patients received adjuvant chemotherapy (25%). Overall survival was 100% with a median follow-up of 8 years (6 -10 years).

Conclusion: Multidisciplinary collaboration is the key of therapeutic success of CMN.

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Vol 2-3 Case Report

Acute Onset of Persistent Tachycardia in a Patient with Duchenne Muscular Dystrophy

Madison Nation, MD1, Megyn Beyer, DO2, Margaret Ellis, DO, MSPH3, Nicholas M. Potisek, MD4*

1Pediatric Residency

4*Department of Pediatrics, Wake Forest Baptist Medical Center Winston-Salem, NC

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Vol 2-3 Mini Review

Human exfoliated deciduous teeth and oral mucosa: promising applications in tissue regeneration

Marta Cristaldi1, Rodolfo Mauceri1, Laura Tomasello2, Giuseppe Pizzolanti2, Giovanni Zito5, Riccardo Alessandro3,4, Carla Giordano2*, Giuseppina Campisi1

1Department of Surgical, Oncological and Oral Sciences, University of Palermo, Palermo, Italy

2Biomedical Department of Internal and Specialist Medicine (DIBIMIS), Laboratory of Regenerative Medicine, Section of Endocrinology, Diabetology and Metabolism, University of Palermo, Palermo, Italy

3Department of Biopathology and Medical Biotechnology, Section of Biology and Genetics, University of Palermo, Palermo, Italy

4Institute of Biomedicine and Molecular Immunology (IBIM), National Research Council, Palermo, Italy

5Advanced Technologies Network (ATeN) Center, University of Palermo, Palermo, Italy

In the last three decades, the constantly increasing need for therapies, efficiently preventing and/or treating human diseases, has raised the interest in Regenerative Medicine (RM). RM is based on employing mesenchymal stem cells (MSCs), that showed to have great proliferation, self-renewal and multi-lineage differentiation potential, in vitro as well as in vivo. The opportunity of an accessible, painless and low-cost reservoir of MSCs constitutes the first important step of a successful regenerative therapy to include in the current clinical practice. Oral cavity has recently demonstrated to contain different MSCs niches: dental pulp from permanent and deciduous teeth, periodontal ligament, dental follicle, apical papilla and mucosa. MSCs from dental pulp of deciduous teeth, naturally lost in pediatric age, and the oral mucosa have shown to be easily harvested and to have a promising regenerative potential. Thus, the aim of the paper is to review the potentialities of human exfoliated deciduous teeth stem cells (SHEDs) and oral mucosa stem cells (OMSCs) in RM, with the purpose of their use as accessible source of MSCs for the future of pediatric patient.

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